Things to arrange beforehand
They say that it is better to put the things in order while you are at home. Of course, the open affairs could make your trip rather uncomfortable and disturbing. That is why check if you end every business at work and inform your dearest and nearest about your departure. In the most countries with the insurance practice, there are the lows as for its use abroad. Check if your medical bills could be covered with your insurance oversees. The information is usually presented at the counseling services or tourist agencies. A great amount of information is available at the internet. Before leaving learn the general information about the crime and security situation, currency, weather forecasts, health conditions, crime level, political life, areas of instability, driving rules, road conditions, unusual laws and traditions, national holidays, aggressive political and social groups and similar issues. While you are in a foreign country, you have to follow the local laws. So, learn as much as it is possible before your departure. For example, in some countries it is forbidden to smoke or drink alcohol in the public places. You could be forced to pay a fine for breaking the rules. If you do not know the local laws, you are not relieved of responsibility. It is great if you follow the world news and media. It allows learning more about the current political and social situation in the country you are going to visit.
So, be informed and enjoy your trip!